产品货号：
Z39010
中文名称：
TOP2A-Specific抗体
英文名称：
Anti-TOP2A-Specific Antibody (Clone#OTI1E11)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TOP2A-Specific Antibody (Clone#OTI1E11) |
| 指标别名 | DNA topoisomerase 2 alpha;TOP2;TOP2A;TOP2A-Specific;TP2A |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | TOP2A |
| 克隆号 | OTI1E11 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Human recombinant protein fragment corresponding to amino acids 1100-1531 of human TOP2A(NP_001058) produced in E.coli. |
| 实际分子量 | 174.2KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | This gene encodes a DNA topoisomerase,an enzyme that controls and alters the topologic states of DNA during transcription.This nuclear enzyme is involved in processes such as chromosome condensation,chromatid separation,and the relief of torsional stress that occurs during DNA transcription and replication.It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another,thus altering the topology of DNA.Two forms of this enzyme exist as likely products of a gene duplication event.The gene encoding this form,alpha,is localized to chromosome 17 and the beta gene is localized to chromosome 3.The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance.Reduced activity of this enzyme may also play a role in ataxia-telangiectasia.[provided by RefSeq,Jul |
| Uniprot ID | P11388 |
| 基因名全称 | topoisomerase(DNA) II alpha 170kDa |
| 蛋白名全称 | DNA topoisomerase 2-alpha |
| 推荐稀释比 | Western blot (WB) 1:2000 |
相关搜索：TOP2A-Specific抗体，TOP2A-Specific单抗，Anti-TOP2A-Specific Antibody (Clone#OTI1E11)